We limit our enrollment to treatments where we can consistently reach back to the patient and their family to assess efficacy.
EVERYTHING YOU HAVE TO KNOW ABOUT STEM CELLS
We strongly recommend you read it before considering a stem cell treatment.
Stem cell therapeutics work very well for most orthopedic applications, and degradative or degenerative damage to joints and cartilage.
Stem cells control the body’s ability to regenerate and repair. Stem cells also produce an array of signaling molecules and growth factors that can stimulate amplify healing activities.
With this power to trigger cellular proliferation and grow into different cell types, stem cells provide a simple and efficient solution to the challenge of repairing and maintaining a diverse population of cell types.
It is important to recognize that there are many types of stem cells, each with unique capabilities and each with different clinical and ethical considerations.
The most powerful cells are pluripotent stem cells- cells that can differentiate into every tissue type. Embryonic stem cells are an example of pluripotent cells. These cells are highly controversial, are infrequently used.
Novastem does not use embryonic stem cells in any research or clinical activities.
More recently, scientists developed a way to genetically modify adult skin cells to ‘revert’ them back to an embryonic stage. These induced pluripotent cells (IPScs) have exciting therapeutic potential and were the subject of the 2012 Nobel prize. However, risks associated with genetic modification and the potential for uncontrolled cellular proliferation has slowed clinical development.
To date, only a few patients have been treated with IPSCs.
Most stem cells used clinically today are multipotent stem cells, meaning that they can differentiate into several tissue types, but not all. Multipotent stem cells can be found in most tissue types throughout the body, and in general, the origin of the stem cell will largely predict the type of tissue it is most well suited to repair/ regenerate. Fat derived stem cells, for example, do not readily differentiate into liver cells. Similarly, hematopoietic stem cells from the marrow cannot form cartilage tissue.