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Learn more about the scientific basis of our work at Novastem here.
Novastem.
Clinic specializing in Stem Cell Treatments
Scientific information about stem cell treatment.
Scientific information about stem cell treatment.
Stem cell treatment is an alternative treatment for conditions and diseases based on the theory that the best repair agent is within the affected organism itself, therefore your healthy cells are able to provide the solution to your own conditions, avoiding rejection or complications.
For more information on how we can help you, schedule an appointment with one of our specialists.
What do we know at
What are mesenchymal stem cells (MSC)?
Mesenchymal stem cells (MSCs) are multipotent stem cells found in bone marrow that are important for making and repairing skeletal tissues, such as cartilage, bone and fat found in bone marrow. These should not be confused with hematopoietic (blood) stem cells that are also found in the bone marrow and form our blood.
MSCs make up a very small fraction of all the cells in our bone marrow, but researchers have been able to isolate MSCs so that they can be studied.
Recent studies have suggested that MSCs are important in creating a specific environment or “home” for blood stem cells in the bone marrow.
What is platelet-rich plasma?
Platelets are cell fragments in the blood and are best known for their ability to help blood clot. However, they also contain a variety of proteins called growth factors.
Platelet-rich plasma therapy is based on the notion that these growth factors can aid healing. The process, which uses the person’s own blood, involves separating the blood cells from the plasma, the liquid part of the blood. The process increases the amount of platelets, which are then returned to the plasma.
This plasma now contains a higher than normal concentration of platelets, which a physician can inject into an area damaged by disease or injury.
Research has shown that platelet-rich plasma can help with knee pain and may be particularly helpful for those who have not had success with other treatments.
Platelet-rich plasma has been used to treat:
instability and pain in various joints.
injuries throughout the body, including knee, shoulder, elbow and other joints.
- osteoarthritis
- carpal tunnel syndrome
- chronic pain conditions
- sprains and strains
Although researchers think growth factors play a role in healing, it’s not clear precisely how platelet-rich plasma helps healing. It doesn’t work for everyone, but people who see improvement generally experience healing over several weeks.
Among people who experience a reduction in pain after treatment with protein-rich plasma, the results are usually permanent. However, some people may need follow-up treatments if pain returns.
Other studies have found that platelet-rich plasma can effectively treat injuries in other areas of the body. For example, a 2006 study found a 60 percent improvement in elbow tendonitis in people who underwent platelet-rich plasma injections.
Most studies have found few or no side effects and suggest that platelet-rich plasma is a safe and less invasive alternative to knee surgery. Because the injections involve the person’s own blood, an allergic or other adverse reaction is less likely to occur than with other injections.
What are Wharton’s jelly-derived mesenchymal stem cells?
During pregnancy, the placenta and the growing fetus are connected by the Umbilical Cord. This cord prevents the umbilical vessels from bending, compressing, or twisting during fetal movement, ensuring adequate blood supply to the fetus ( Kim et al., 2013 ). Anatomically, the human umbilical cord comprises an outer layer of amniotic epithelium enclosing a vein and two arteries embedded within mucoid connective tissue. The mucoid connective tissue enclosing the three umbilical vessels is known as “Wharton’s jelly”. It was first described by Wharton (1656) and is composed mainly of collagen and proteoglycans. The discovery of Wharton’s jelly (WJ) providing a source of MSC was first highlighted in McElreavey et al. (1991). It was not until 2004 that the first report providing strong evidence that WJ stromal cells can be classified as MSCs was published ( Wang et al., 2004 ).
Wharton’s jelly-derived mesenchymal stem cells (WJ-MSCs) are a novel and promising strategy for tissue engineering due to their ability to differentiate into many cell types.
Wharton’s jelly mesenchymal stem cells (WJ-MSCs) are characterized by rapid proliferation, stable biological properties, low immunogenicity, and ease of isolation. In addition, WJ-MSCs can secrete a large number of cytokines and have no tumorigenic effects. Studies have shown that stem cells isolated from Wharton’s jelly have the ability to differentiate into adipocytes, osteocytes, chondrocytes, neurons and oligodendrocytes.
What is Platelet Lysate?
Platelets naturally release their growth factors in a slow and programmed manner to aid healing. However, there are times when a physician needs all of the growth factors contained in the platelets to be immediately available to the area to speed healing. In addition, there are areas of the body where the use of platelet-rich plasma (PRP) can cause too much inflammation. Platelet lysate is then created as a solution by breaking up these platelets to allow all the growth factors to be immediately released into the body.
Novastem. A clinic of competence in stem cell treatment.
Over the years, numerous attempts have been made to discover medical and non-medical treatment options for this condition. In some cases, medical treatments have led to increased survival and improved quality of life, and options for non-medical therapies have emerged.
Novastem’s goal with our treatments is to reverse the lack of functionality, eliminating pain and allowing you to enjoy 100% of daily activities and life again.
In Novastem we have the strictest protocols of acceptance to treat a patient laboratory studies are performed before each therapy, we use for joint injuries injection of mesenchymal stem cells derived from bone marrow with platelet-rich plasma or PRP, the treatment is guided by ultrasound and / or fluoroscopy of a single day with or without anesthesia for direct application in the area to be treated.
For more information on how we can help you, schedule an appointment with one of our specialists.